Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 11/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FHIT | P49789 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464927 | 0.91 | CHEK2 (0.49) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL5217725 | 0.81 | CHEK2 (0.87) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL8600314 | 0.79 | CHEK2 (0.60) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL20982644 | 0.78 | NR4A2 (0.86) | CHEK2NR4A2MMP2MMP9MMP8 | |
| SCHEMBL3167456 | 0.77 | CHEK2 (0.57) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL20982607 | 0.77 | CHEK2 (0.63) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL5219768 | 0.77 | NR4A2 (0.83) | CHEK2NR4A2MMP2MMP9MMP8 | |
| SCHEMBL4259320 | 0.76 | PKN1 (0.77) | CHEK2NR4A2MMP2MMP9MMP8 | |
| SCHEMBL5221558 | 0.76 | NPBWR1 (0.80) | CHEK2NPBWR1MMP2MMP9MMP8 | |
| SCHEMBL3178116 | 0.76 | CHEK2 (0.78) | CHEK2NR4A2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |