SCHEMBL8602000

SCHEMBL8602000

CCCCC(CC)C(=O)NOC(=O)CCC(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.56
CA1 P00915 5/20 0.56
MAPK1 P28482 2/20 0.44
BIRC2 Q13490 1/20 0.43
TSHR P16473 4/20 0.42
USP2 O75604 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23881998 0.85 CA2 (0.61) CA2CA1MAPK1TSHRUSP2
SCHEMBL29063420 0.79 CA2 (0.53) CA2CA1MAPK1BIRC2USP2
SCHEMBL29062790 0.79 CA2 (0.53) CA2CA1MAPK1BIRC2USP2
SCHEMBL29063188 0.78 CA2 (0.50) CA2CA1MAPK1BIRC2USP2
SCHEMBL23801208 0.76 BIRC2 (0.64) CA2CA1MAPK1BIRC2TSHR
SCHEMBL28399283 0.74 CA2 (0.54) CA2CA1MAPK1USP2CA7
2-Ethylhexanoic Acid SCHEMBL28067045 0.73 CA2 (0.65) CA2CA1MAPK1TSHRMEN1
SCHEMBL17439956 0.72 CA2 (1.00) CA2CA1MAPK1TSHRUSP2
SCHEMBL8460512 0.72 CA2 (0.73) CA2CA1MAPK1TSHRUSP2
SCHEMBL1428501 0.72 TSHR (0.48) CA2CA1MAPK1TSHRUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5798331-A AGROCHEMICAL FORMULATIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-08-25 US disclosed