SCHEMBL8602154

SCHEMBL8602154

CCCCCCCCCCCCCCNC(=O)Nc1cc(Br)c(O)c(Br)c1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 15/20 0.60
ALDH1A1 P00352 1/20 0.60
HTT P42858 1/20 0.60
EPHX2 P34913 3/20 0.54
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603314 1.00 EPHX1 (0.60) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL4356041 0.98 EPHX1 (0.57) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL6225668 0.86 ALDH1A1 (0.55) EPHX1ALDH1A1HTTEPHX2
SCHEMBL8387679 0.85 EPHX1 (0.63) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL8756853 0.84 EPHX2 (0.63) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL8602435 0.82 EPHX2 (0.69) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL8602439 0.82 EPHX2 (0.69) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL4347034 0.81 EPHX2 (0.67) EPHX1ALDH1A1HTTEPHX2HDAC1
SCHEMBL4350358 0.81 SMN1; SMN2 (0.50) ALDH1A1HTT
SCHEMBL4358445 0.81 EPHX1 (0.57) EPHX1ALDH1A1HTTEPHX2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709225-B1 Reversible multi-color thermal recording medium JUJO PAPER CO LTD (JP) 1998-08-05 EP disclosed
US-5710094-A HEAT RESISTANT ORGANIC UREA OR THIOUREA COLOR DEVELOPER NIPPON PAPER INDUSTRIES CO. LTD. (JP) 1998-01-20 US disclosed
EP-0709225-A1 Reversible multi-color thermal recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-05-01 EP disclosed
US-5500188-A Device for photoresponsive detection and discrimination MOLECULAR DEVICES CORPORATION (US) 1996-03-19 US disclosed
EP-0172892-B1 METHOD AND DEVICE EMPLOYING PHOTORESPONSIVE SEMICONDUCTOR ELECTRODE FOR DETERMINING ANALYTE Molecular Devices Corporation (US) 1991-07-24 EP disclosed
EP-0172892-A4 METHOD AND DEVICE EMPLOYING PHOTORESPONSIVE SEMICONDUCTOR ELECTRODE FOR DETERMINING ANALYTE. MOLECULAR DEVICES CORP (US) 1986-08-21 EP disclosed
US-4591550-A Device having photoresponsive electrode for determining analytes including ligands and antibodies MOLECULAR DEVICES CORPORATION (US) 1986-05-27 US disclosed
EP-0172892-A1 METHOD AND DEVICE EMPLOYING PHOTORESPONSIVE SEMICONDUCTOR ELECTRODE FOR DETERMINING ANALYTE. MOLECULAR DEVICES CORP (US) 1986-03-05 EP disclosed
WO-1985004018-A1 METHOD AND DEVICE EMPLOYING PHOTORESPONSIVE SEMICONDUCTOR ELECTRODE FOR DETERMINING ANALYTE MOLECULAR DEVICES CORPORATION (US) 1985-09-12 WO disclosed