Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 16/20 | 0.43 |
| ▸ | CA9 | Q16790 | 16/20 | 0.43 |
| ▸ | CA2 | P00918 | 14/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | GRK5 | P34947 | 2/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA7 | P43166 | 7/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773301 | 0.81 | RET (0.50) | CA12CA9CA2RETGRK5 | |
| SCHEMBL7777789 | 0.77 | CA12 (0.40) | CA12CA9CA2RETGRK5 | |
| SCHEMBL7287476 | 0.77 | CA12 (0.58) | CA12CA9CA2RETGRK5 | |
| SCHEMBL29700163 | 0.75 | RET (0.46) | CA12CA9CA2RETGRK5 | |
| SCHEMBL8084646 | 0.75 | RET (0.46) | CA12CA9CA2RETGRK5 | |
| SCHEMBL7778266 | 0.75 | RET (0.46) | CA12CA9CA2RETGRK5 | |
| SCHEMBL6275367 | 0.71 | CA2 (0.41) | CA12CA9CA2CA1CA7 | |
| SCHEMBL7777768 | 0.70 | CA12 (0.44) | CA12CA9CA2RETGRK5 | |
| SCHEMBL8134119 | 0.69 | PTK2 (0.35) | CA2KDM4EPTK2CYP1A2 | |
| SCHEMBL31389208 | 0.67 | CYP1A2 (0.58) | CA12CA9CA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744425-A | POSTEMERGENCE, PREEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5723415-A | AGRICULTURAL HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5716905-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| US-5716906-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |