Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | FAP | Q12884 | 1/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 6/20 | 0.59 |
| ▸ | REN | P00797 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PEPD | P12955 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602481 | 1.00 | DPP4 (0.61) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL30314724 | 0.88 | DPP4 (0.63) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL6240873 | 0.87 | DPP4 (0.61) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL12343823 | 0.87 | DPP4 (0.61) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL11339157 | 0.86 | DPP4 (0.60) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29405754 | 0.85 | ACE (0.56) | DPP4ACERENKDM4EF2 | |
| SCHEMBL2739551 | 0.85 | ACE (0.56) | DPP4ACERENKDM4EF2 | |
| SCHEMBL29380436 | 0.85 | ACE (0.56) | DPP4ACERENKDM4EF2 | |
| SCHEMBL556799 | 0.85 | DPP4 (0.65) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL12343831 | 0.84 | DPP4 (0.58) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828851-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1998-03-18 | — | — | EP | claimed |
| EP-0828851-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996035805-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1996-11-14 | — | — | WO | disclosed |