Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 8/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766452 | 0.86 | CDA (0.36) | CDAGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL30504020 | 0.86 | GAA (0.33) | GAAMAPTATAD2ALDH1A1 | |
| SCHEMBL31544543 | 0.80 | GAA (0.31) | GAAMAPTATAD2ALDH1A1 | |
| SCHEMBL15533724 | 0.80 | GAA (0.32) | CDAGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL15810662 | 0.76 | GAA (0.35) | GAAMAPTLMNASMN1; SMN2ATAD2 | |
| SCHEMBL15740124 | 0.73 | PNP (0.45) | GAAMAPTLMNASMN1; SMN2ATAD2 | |
| SCHEMBL774016 | 0.71 | PNP (0.44) | MAPTLMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL10226283 | 0.71 | PNP (0.44) | MAPTLMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL64635 | 0.71 | PNP (0.44) | MAPTLMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL21847661 | 0.71 | PNP (0.44) | MAPTLMNASMN1; SMN2TSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432792-A1 | N- [ (2 ' R) -2 ' -DEOXY-2 ' -FLUORO-2 ' -METHYL-P-PHENYL-5 ' -URIDYLYL]-L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION | Pharmasset, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135569-A1 | N- [ (2 ' R) -2 ' -DEOXY-2 ' -FLUORO-2 ' -METHYL-P-PHENYL-5 ' -URIDYLYL] -L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION | PHARMASSET, INC. (US) | 2010-11-25 | — | — | WO | disclosed |