Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | CDA | P32320 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504020 | 0.81 | GAA (0.33) | GAAMAPTATAD2 | |
| SCHEMBL766452 | 0.81 | CDA (0.36) | GAAMAPTCDALMNASMN1; SMN2 | |
| SCHEMBL860292 | 0.80 | CDA (0.33) | GAAMAPTATAD2CDALMNA | |
| SCHEMBL31544543 | 0.78 | GAA (0.31) | GAAMAPTATAD2 | |
| SCHEMBL15810662 | 0.73 | GAA (0.35) | GAAMAPTATAD2LMNASMN1; SMN2 | |
| SCHEMBL23892079 | 0.72 | TK1 (0.41) | LMNASMN1; SMN2TK1 | |
| SCHEMBL12642442 | 0.72 | TK1 (0.41) | LMNASMN1; SMN2TK1 | |
| SCHEMBL658719 | 0.72 | TK1 (0.41) | LMNASMN1; SMN2TK1 | |
| SCHEMBL2641583 | 0.72 | TK1 (0.41) | LMNASMN1; SMN2TK1 | |
| SCHEMBL774016 | 0.71 | PNP (0.44) | MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074412-A1 | CRYSTAL FORM OF NUCLEOSIDE INHIBITOR OF HCV | Janssen Sciences Ireland UC (IE) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015077966-A1 | CRYSTAL FORM OF NUCLEOSIDE INHIBITOR OF HCV | JANSSEN R&D IRELAND (IE) | 2015-06-04 | — | — | WO | disclosed |
| EP-2861611-A1 | URACYL SPIROOXETANE NUCLEOSIDES | Janssen Sciences Ireland UC (IE) | 2015-04-22 | — | — | EP | disclosed |
| WO-2013174962-A1 | URACYL SPIROOXETANE NUCLEOSIDES | JANSSEN R&D IRELAND (IE) | 2013-11-28 | — | — | WO | disclosed |