Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nafoxidine SCHEMBL153125 | 0.78 | EBP (1.00) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Nafoxidine SCHEMBL29494604 | 0.78 | EBP (1.00) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Nafoxidine SCHEMBL10563464 | 0.78 | EBP (1.00) | EBPSIGMAR1HRH3LTA4HESR1 | |
| SCHEMBL8015672 | 0.78 | EBP (0.88) | EBPSIGMAR1HRH3LTA4HESR1 | |
| SCHEMBL7105763 | 0.78 | ESR1 (0.72) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Nafoxidine SCHEMBL29562423 | 0.77 | EBP (0.98) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Nafoxidine SCHEMBL115778 | 0.77 | EBP (0.98) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Nafoxidine SCHEMBL8430193 | 0.77 | EBP (0.98) | EBPSIGMAR1HRH3LTA4HESR1 | |
| Hydrochloric Acid SCHEMBL7153807 | 0.77 | ESR1 (0.71) | EBPSIGMAR1HRH3LTA4HESR1 | |
| SCHEMBL7109994 | 0.77 | EBP (0.61) | EBPSIGMAR1HRH3LTA4HBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826670-A1 | Naphthalene compounds, intermediates, formulations, and methods | ELI LILLY AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |