Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585067 | 0.88 | GAA (0.56) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL27606754 | 0.85 | GAA (0.59) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL31527868 | 0.85 | GAA (0.73) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL1791238 | 0.85 | GAA (0.73) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL11326923 | 0.81 | ALDH1A1 (0.61) | GAALMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29676195 | 0.81 | ALDH1A1 (0.61) | GAALMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1639715 | 0.80 | GAA (0.59) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL744526 | 0.77 | GAA (0.67) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL29612239 | 0.77 | GAA (0.67) | GAALMNAMCL1KMT2ACYP2C19 | |
| SCHEMBL19183582 | 0.76 | GAA (0.48) | GAALMNAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726314-A | ACETYLCHOLINESTERASE INHIBITORS AS NERVE AGENT ANTIDOTES | GEORGIA TECH RESEARCH CORP. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5714615-A | ACETYLCHOLINESTERASE ENZYME INHIBITOR, STIMULATE NICOTINIC RECEPTORS IN CENTRAL NERVOUS SYSTEM | GEORGIA TECH RESEARCH CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| WO-1995021822-A1 | PYRIDINIUM COMPOUNDS | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-08-17 | — | — | WO | disclosed |