Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692636 | 0.81 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14692637 | 0.81 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4804215 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29870513 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4804208 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL25196440 | 0.76 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL2807601 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2807599 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30807155 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14692453 | 0.75 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |