SCHEMBL2807599

SCHEMBL2807599

COc1ccc(/C=C/C(=O)c2ccccc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 1.00
MAOB P27338 7/20 1.00
MAOA P21397 4/20 1.00
CYP2C19 P33261 3/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
CASP3 P42574 1/20 1.00
SENP8 Q96LD8 1/20 1.00
SENP7 Q9BQF6 1/20 1.00
SENP6 Q9GZR1 1/20 1.00
MEN1 O00255 4/20 0.74
MAPK1 P28482 4/20 0.74
KMT2A Q03164 4/20 0.74
ABCG2 Q9UNQ0 4/20 0.74
LMNA P02545 3/20 0.74
CYP3A4 P08684 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
APP P05067 1/20 0.74
ALDH1A1 P00352 3/20 0.70
HPGD P15428 3/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2807601 1.00 MAPT (1.00) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL30807155 1.00 MAPT (1.00) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL25202062 0.89 MAOB (1.00) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL25219836 0.87 MAOB (0.89) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL25191373 0.87 MAOB (0.89) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL25233412 0.87 MAOB (0.89) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL25195966 0.87 MAOB (0.89) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL7196545 0.87 MAOB (0.80) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL31234600 0.87 MAOB (0.80) MAPTMAOBMAOACYP2C19CYP2D6
SCHEMBL7196541 0.87 MAOB (0.80) MAPTMAOBMAOACYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2790658-B1 METHOD OF STRENGTHENING HAIR FIBRES UNILEVER PLC (GB) 2017-08-16 EP claimed
US-20140366906-A1 HAIR COLOUR COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2014-12-18 US claimed
US-20140335038-A1 METHOD OF STRENGTHENING HAIR FIBRES CONOPCO, INC., D/B/A UNILEVER (US) 2014-11-13 US claimed
EP-2790658-A2 METHOD OF STRENGTHENING HAIR FIBRES Unilever Plc. (GB) 2014-10-22 EP claimed
EP-2787953-A2 HAIR COLOUR COMPOSITION Unilever PLC, a company registered in England and Wales under company no. 41424 (GB) 2014-10-15 EP claimed
WO-2014095318-A2 METHOD OF PREVENTING HAIR FIBRE DAMAGE UNILEVER PLC (GB) 2014-06-26 WO claimed
WO-2013087644-A2 METHOD OF STRENGTHENING HAIR FIBRES UNILEVER PLC (GB) 2013-06-20 WO claimed
WO-2013083510-A2 HAIR COLOUR COMPOSITION UNILEVER PLC (GB) 2013-06-13 WO claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-20240316118-A1 ANTIVIRAL NASAL SPRAY FLAVONOIDS?BEE PROPOLIS MCCAFFREY STEPHEN MARK (AU) 2024-09-26 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2024035085-A1 NOVEL COMPOUND, AND COMPOSITION FOR PREVENTING OR TREATING HER2-POSITIVE CANCER, COMPRISING SAME 이화여자대학교 산학협력단 2024-02-15 WO disclosed
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof EASTMAN CHEMICAL COMPANY 2007-11-01 US disclosed
WO-2007115181-A2 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEMICAL COMPANY (US) 2007-10-11 WO disclosed
WO-2007082178-A2 PROSTAGLANDIN REDUCTASE INHIBITORS ABGENOMICS CORPORATION (TW) 2007-07-19 WO disclosed
EP-1764363-A2 SUBSTITUTED ACETOPHENONEDERIVATIVES Riemser Arzneimittel AG (DE) 2007-03-21 EP disclosed
US-20060142303-A1 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2006-06-29 US disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof ABCC4, NCOA4, NR4A3 MAPT 4566/4885MAOB 1213/4885MAOA 1628/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOB 1004/4885MAOA 1902/4885
US-20060142303-A1 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents LIPC, CYP46A1, HMGCR MAPT 4801/4885MAOB 2303/4885MAOA 3304/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.