SCHEMBL8603262

SCHEMBL8603262

O=S(=O)(O)CCCOCCOc1ccsc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.37
S1PR1 P21453 1/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
BRCA1 P38398 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
PKM P14618 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2885917 0.92 S1PR1 (0.39) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL8605088 0.91 S1PR1 (0.34) RARBS1PR1ALDH1A1LMNAPOLB
SCHEMBL2887394 0.88 ALDH1A1 (0.41) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2884338 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2885629 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2886289 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2885494 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2882517 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL2886440 0.86 ALDH1A1 (0.43) S1PR1ALDH1A1LMNAPOLBRAB9A
SCHEMBL1642775 0.84 S1PR1 (0.37) S1PR1ALDH1A1LMNAPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459255-B1 Method for suppression of electrification HITACHI LTD (JP) 1998-03-18 EP disclosed
US-5589270-A Processed substrate obtained by a process for effecting suppression of electrification HITACHI, LTD. (JP) 1996-12-31 US disclosed
US-5437893-A Method for suppression of electrification HITACHI, LTD (JP) 1995-08-01 US disclosed
US-5256454-A Method for suppression of electrification HITACHI, LTD. (JP) 1993-10-26 US disclosed
EP-0459255-A2 Method for suppression of electrification HITACHI, LTD. (JP) 1991-12-04 EP disclosed