Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906004 | 0.85 | NOTUM (0.40) | IDO1TDO2ARNOTUM | |
| SCHEMBL9401918 | 0.79 | AR (0.37) | IDO1TDO2ARNOTUM | |
| SCHEMBL5906245 | 0.79 | AR (0.49) | ARNOTUM | |
| SCHEMBL5906416 | 0.78 | NOTUM (0.53) | IDO1TDO2ARNOTUM | |
| SCHEMBL9401981 | 0.78 | NOTUM (0.35) | IDO1TDO2ARNOTUM | |
| SCHEMBL8603436 | 0.78 | IDO1 (0.51) | IDO1TDO2ARNOTUM | |
| SCHEMBL2161285 | 0.73 | ATM (0.47) | NOTUM | |
| SCHEMBL2161237 | 0.72 | HTT (0.58) | ARNOTUM | |
| SCHEMBL5906067 | 0.71 | IDO1 (0.41) | IDO1TDO2NOTUM | |
| SCHEMBL9293712 | 0.70 | PDE2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0643049-B1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5502204-A | REACTING WITH ETHYLENE OXIDE DERIVATIVE | NIHON BAYER AGROCHEM K.K. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0643049-A1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-03-15 | — | — | EP | disclosed |