SCHEMBL9401918

SCHEMBL9401918

O=c1[nH]nnn1-c1ccc(C(F)(F)F)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.37
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
KIF11 P52732 7/20 0.35
DAO P14920 1/20 0.35
PDE2A O00408 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5906245 0.88 AR (0.49) ARNOTUM
SCHEMBL5906004 0.88 NOTUM (0.40) ARIDO1TDO2NOTUM
SCHEMBL9401981 0.84 NOTUM (0.35) ARIDO1TDO2NOTUM
SCHEMBL8603436 0.84 IDO1 (0.51) ARIDO1TDO2DAONOTUM
SCHEMBL5906416 0.81 NOTUM (0.53) ARIDO1TDO2NOTUM
SCHEMBL8604065 0.79 IDO1 (0.31) ARIDO1TDO2NOTUM
SCHEMBL9293712 0.79 PDE2A (0.34) PDE2A
SCHEMBL9294622 0.79 EPHX2 (0.40) PDE2A
SCHEMBL2161285 0.76 ATM (0.47) NOTUM
SCHEMBL2161237 0.75 HTT (0.58) ARNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347009-A Herbicidal 1-(3-halo-4-trifluoromethylphenyl) tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0571855-A1 1-(3-Halo-4-trifluoromethyl-phenyl)tetrazolinone derivatives, their preparation and their use as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1993-12-01 EP disclosed