Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602764 | 0.91 | ATM (0.43) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8603779 | 0.91 | RAB9A (0.54) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8604411 | 0.91 | RAB9A (0.54) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8601811 | 0.88 | EPHX1 (0.52) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8603355 | 0.88 | EPHX1 (0.52) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8605647 | 0.88 | EPHX1 (0.52) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8636134 | 0.88 | EPHX1 (0.52) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8603936 | 0.83 | ATM (0.41) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8603993 | 0.83 | ATM (0.47) | ATMRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8604078 | 0.83 | ATM (0.42) | ATMRAB9AKMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733931-A | ANTICHOLESTEROL AGENTS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |