Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797916 | 1.00 | HSD11B1 (0.58) | HSD11B1TNFRSF1APOLBLMNATP53 | |
| SCHEMBL8168214 | 0.91 | POLB (0.51) | HSD11B1TNFRSF1APOLBLMNATP53 | |
| SCHEMBL8682729 | 0.85 | GSK3B (0.64) | MAOBMEN1KMT2A | |
| SCHEMBL7080680 | 0.84 | KMT2A (0.56) | HSD11B1LMNATP53ALDH1A1MEN1 | |
| SCHEMBL28498745 | 0.84 | CA12 (0.62) | HSD11B1MAOBMMP1MMP2MMP9 | |
| SCHEMBL14583488 | 0.84 | CA12 (0.62) | HSD11B1MAOBMMP1MMP2MMP9 | |
| SCHEMBL7080678 | 0.84 | KMT2A (0.56) | HSD11B1LMNATP53ALDH1A1MEN1 | |
| SCHEMBL8606605 | 0.82 | CYP1A2 (0.58) | LMNAMAOBALDH1A1MAOACYP1B1 | |
| SCHEMBL1357937 | 0.82 | MAPT (0.53) | POLBTP53MAOBALDH1A1MAOA | |
| SCHEMBL312612 | 0.81 | MAPT (0.55) | TNFRSF1ALMNAMAOBALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830634-A1 | LIQUID CRYSTAL ALIGNMENT MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of The United Kingdom of Great Britain and Northern I (GB) | 1998-03-25 | — | — | EP | disclosed |
| WO-1997038349-A1 | LIQUID CRYSTAL ALIGNMENT MATERIALS AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1997-10-16 | — | — | WO | disclosed |