Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608641 | 0.92 | GAA (0.54) | GAAALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8608828 | 0.87 | GAA (0.65) | GAAALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8609160 | 0.85 | GAA (0.49) | GAAMAPTKMT2AHPGDPKM | |
| SCHEMBL8606439 | 0.85 | GAA (0.58) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8607305 | 0.83 | GAA (0.54) | GAAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8608313 | 0.83 | GAA (0.54) | GAAALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8606000 | 0.81 | GAA (0.61) | GAAALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8606474 | 0.80 | GAA (0.54) | GAAALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8608693 | 0.80 | GAA (0.46) | GAAMAPTKMT2AHPGDPOLB | |
| SCHEMBL4599326 | 0.79 | KMT2A (0.55) | GAAALDH1A1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |