Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604372 | 0.92 | GAA (0.55) | GAAMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8606000 | 0.90 | GAA (0.61) | GAAMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8608693 | 0.84 | GAA (0.46) | GAAKMT2AMAPTPKMHTT | |
| SCHEMBL8608828 | 0.83 | GAA (0.65) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8607305 | 0.82 | GAA (0.54) | GAAMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8609160 | 0.80 | GAA (0.49) | GAAKMT2AMAPTPKMHTT | |
| SCHEMBL8606439 | 0.80 | GAA (0.58) | GAAMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7097900 | 0.80 | ALDH1A1 (0.60) | GAACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8608313 | 0.79 | GAA (0.54) | GAAMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8606474 | 0.79 | GAA (0.54) | GAAMEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |