Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605121 | 0.85 | HTR2A (0.39) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL8606346 | 0.81 | MEN1 (0.52) | MEN1KMT2ANPSR1ANPEPGAA | |
| SCHEMBL8604219 | 0.78 | POLB (0.49) | MEN1KMT2ANPSR1GAAPOLB | |
| SCHEMBL8606680 | 0.77 | POLB (0.48) | MEN1KMT2ANPSR1ANPEPGAA | |
| SCHEMBL8605755 | 0.77 | POLB (0.48) | MEN1KMT2ANPSR1ANPEPGAA | |
| SCHEMBL8603056 | 0.74 | MEN1 (0.39) | MEN1KMT2AGAALMNAKDM4E | |
| SCHEMBL8606350 | 0.74 | ANPEP (0.45) | MEN1KMT2ANPSR1ANPEPGAA | |
| SCHEMBL8604607 | 0.73 | TSHR (0.36) | ANPEPGAAPOLB | |
| SCHEMBL14064101 | 0.72 | MEN1 (0.62) | MEN1KMT2ANPSR1GAAPOLB | |
| SCHEMBL3134001 | 0.71 | MEN1 (0.60) | MEN1KMT2ANPSR1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590009-B1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | UPJOHN CO (US) | 1998-03-18 | — | — | EP | claimed |
| US-5347029-A | Dialkyl (dialkoxyphosphinyl)methyl phosphates as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| EP-0590009-A1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | claimed |
| EP-0590009-B1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | UPJOHN CO (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5347029-A | Dialkyl (dialkoxyphosphinyl)methyl phosphates as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0590009-A1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022559-A1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |