Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709548 | 0.88 | PPARD (0.37) | PPARDGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19420896 | 0.81 | TSHR (0.46) | TSHRPPARDGAACYP3A4CYP2C9 | |
| SCHEMBL19405868 | 0.73 | TSHR (0.38) | TSHRPPARDGAAPOLB | |
| SCHEMBL19405741 | 0.73 | TSHR (0.38) | TSHRPPARDGAAPOLB | |
| SCHEMBL8604465 | 0.73 | MEN1 (0.47) | GAAPOLBANPEP | |
| SCHEMBL8606663 | 0.71 | GAA (0.41) | TSHRGAA | |
| SCHEMBL8603774 | 0.69 | ANPEP (0.41) | TSHRPOLBANPEP | |
| SCHEMBL1394238 | 0.67 | PPARD (0.42) | TSHRPPARDGAACYP3A4CYP2C9 | |
| SCHEMBL31222198 | 0.65 | SMPD1 (0.37) | CYP3A4 | |
| SCHEMBL15532056 | 0.65 | PPARD (0.65) | TSHRPPARDGAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590009-B1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | UPJOHN CO (US) | 1998-03-18 | — | — | EP | claimed |
| US-5347029-A | Dialkyl (dialkoxyphosphinyl)methyl phosphates as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| EP-0590009-B1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | UPJOHN CO (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5347029-A | Dialkyl (dialkoxyphosphinyl)methyl phosphates as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0590009-A1 | DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |