Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700517 | 0.82 | POLB (0.65) | POLBTDP1ALDH1A1EGLN1LMNA | |
| SCHEMBL1902851 | 0.80 | KDM4E (0.68) | POLBTDP1ALDH1A1KMT2ADHODH | |
| SCHEMBL26783213 | 0.77 | TDP1 (0.56) | POLBTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL26451268 | 0.77 | TDP1 (0.66) | POLBTDP1ALDH1A1EGLN1LMNA | |
| SCHEMBL9374743 | 0.77 | TDP1 (0.66) | POLBTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL4132618 | 0.77 | ALDH1A1 (0.64) | POLBTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL19669288 | 0.76 | TDP1 (0.71) | POLBTDP1ALDH1A1EGLN1LMNA | |
| SCHEMBL2588443 | 0.76 | ALDH1A1 (0.72) | POLBTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL21018016 | 0.76 | TDP1 (0.66) | POLBTDP1ALDH1A1EGLN1LMNA | |
| SCHEMBL22717488 | 0.75 | POLB (0.56) | POLBTDP1ALDH1A1EGLN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828713-A2 | PYRIDINE-MICROBICIDES | CIBA-GEIGY AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037472-A2 | PYRIDINE-MICROBICIDES | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |