SCHEMBL8605262

SCHEMBL8605262

NC(CC(=O)NC(Cc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACE P12821 5/20 0.62
ECE1 P42892 1/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
PTGS1 P23219 1/20 0.59
XIAP P98170 1/20 0.59
SLC7A5 Q01650 1/20 0.59
SLC1A3 P43003 3/20 0.55
SLC1A2 P43004 3/20 0.55
SLC1A1 P43005 3/20 0.55
MME P08473 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
NAALAD2 Q9Y3Q0 1/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694682 1.00 ACE (0.62) ACEECE1ALPIPKMPTGS1
SCHEMBL18222570 1.00 ACE (0.62) ACEECE1ALPIPKMPTGS1
SCHEMBL9300989 1.00 ACE (0.62) ACEECE1ALPIPKMPTGS1
SCHEMBL6830447 1.00 ACE (0.62) ACEECE1ALPIPKMPTGS1
SCHEMBL8213279 0.98 ACE (0.60) ACEECE1ALPIPKMPTGS1
SCHEMBL27516456 0.91 MME (0.54) ACEECE1ALPIPKMPTGS1
SCHEMBL7999080 0.91 MME (0.54) ACEECE1ALPIPKMPTGS1
Potassium Ion SCHEMBL8213281 0.88 ALPI (0.53) ACEECE1ALPIPKMPTGS1
SCHEMBL18222587 0.88 ACE (0.64) ACESLC7A5MMENAALAD2
SCHEMBL11406714 0.87 ATM (0.58) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297560-B1 Imides; a process for their production and a process for the production of dipeptides using them AJINOMOTO KK (JP) 1998-03-04 EP claimed
EP-0327030-B1 Method for producing alpha-aspartylphenylalanine derivatives AJINOMOTO KK (JP) 1995-01-25 EP claimed
US-4942255-A ISOMERIZATION WITH A BASIC COMPOUND IN AN ALCOHOLIC SOLVENT TO PREVENT PRECIPITATION OF SALTS AJINOMOTO CO., INC. (JP) 1990-07-17 US claimed
EP-0327030-A2 Method for producing alpha-aspartylphenylalanine derivatives AJINOMOTO CO., INC. (JP) 1989-08-09 EP claimed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP claimed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US claimed
JP-1258657-A None JP disclosed
JP-1294690-A None JP disclosed
JP-61277696-A None JP disclosed
EP-0297560-B1 Imides; a process for their production and a process for the production of dipeptides using them AJINOMOTO KK (JP) 1998-03-04 EP disclosed
EP-0327030-B1 Method for producing alpha-aspartylphenylalanine derivatives AJINOMOTO KK (JP) 1995-01-25 EP disclosed
EP-0327030-A3 METHOD FOR PRODUCING ALPHA-ASPARTYLPHENYLALANINE DERIVATIVES AJINOMOTO CO., INC. (JP) 1991-03-27 EP disclosed
US-4942255-A ISOMERIZATION WITH A BASIC COMPOUND IN AN ALCOHOLIC SOLVENT TO PREVENT PRECIPITATION OF SALTS AJINOMOTO CO., INC. (JP) 1990-07-17 US disclosed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP disclosed
EP-0297560-A2 Imides; a process for their production and a process for the production of dipeptides using them Ajinomoto Co., Inc. (JP) 1989-01-04 EP disclosed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US disclosed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US disclosed
US-4673744-A IN ALCOHOL SOLVENT AJINOMOTO CO., INC. (JP) 1987-06-16 US disclosed
JP-S61277696-A METHOD FOR CONVERTING BETA-ASPARTYLPHENYLALANINE DERIVATIVE INTO ALPHA-ASPARTYLPHENYLALANINE DERIVATIVE AJINOMOTO CO INC 1986-12-08 JP disclosed
US-4017472-A Process for isolation of aspartyl dipeptide esters G. D. SEARLE & CO. (US) 1977-04-12 US disclosed