Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.62 |
| ▸ | ECE1 | P42892 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694682 | 1.00 | ACE (0.62) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL18222570 | 1.00 | ACE (0.62) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL6830447 | 1.00 | ACE (0.62) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL8605262 | 1.00 | ACE (0.62) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL8213279 | 0.98 | ACE (0.60) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL27516456 | 0.91 | MME (0.54) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL7999080 | 0.91 | MME (0.54) | ACEECE1ALPIPKMPTGS1 | |
| Potassium Ion SCHEMBL8213281 | 0.88 | ALPI (0.53) | ACEECE1ALPIPKMPTGS1 | |
| SCHEMBL18222587 | 0.88 | ACE (0.64) | ACESLC7A5MMENAALAD2 | |
| SCHEMBL11406714 | 0.87 | ATM (0.58) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032212-C | N-protected alpha-L-aspartyl-L-methyl phenylalaninate | MITSUI TOATSU CHEMICALS (JP) | 1996-07-03 | — | — | CN | disclosed |
| EP-0334236-B1 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |
| CN-1036581-A | N-is protected the preparation method of 2-L-aspartyl-L-phenylalanine methyl esters | MITSUI TOATSU CHEMICALS (JP) | 1989-10-25 | — | — | CN | disclosed |
| EP-0334236-A2 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-27 | — | — | EP | disclosed |
| EP-0270345-A2 | Preparation of alpha-L-aspartyl-L-phenyl-alanine methyl ester or hydrohalide thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-08 | — | — | EP | disclosed |