SCHEMBL86054

SCHEMBL86054

O=C1CCSc2c1ccc1ccccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.40
CYP19A1 P11511 1/20 0.38
KDM4E B2RXH2 5/20 0.37
HTT P42858 4/20 0.37
PAX8 Q06710 1/20 0.37
ALDH1A1 P00352 8/20 0.37
HSD17B10 Q99714 4/20 0.37
TSHR P16473 2/20 0.37
CYP2A6 P11509 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPGD P15428 4/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2C19 P33261 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
HIF1A Q16665 2/20 0.37
CYP2C9 P11712 2/20 0.37
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87109 0.82 DNMT1 (0.42) DNMT1CYP19A1KDM4EHTTPAX8
SCHEMBL14052699 0.74 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL86218 0.72 ALDH1A1 (0.50) DNMT1KDM4EHTTPAX8ALDH1A1
SCHEMBL14259744 0.71 DNMT1 (0.42) DNMT1CYP19A1KDM4EHTTPAX8
SCHEMBL8359592 0.71 HPGD (0.51) DNMT1CYP19A1KDM4EHTTPAX8
SCHEMBL14259745 0.69 CYP19A1 (0.44) DNMT1CYP19A1KDM4EHTTALDH1A1
SCHEMBL86216 0.68 VHL (0.54) KDM4EHTTALDH1A1HSD17B10TSHR
SCHEMBL6924 0.68 NOTUM (0.39) KDM4EHTTALDH1A1CYP2A6MEN1
SCHEMBL5635241 0.68 MEN1 (0.47) KDM4EHTTALDH1A1CYP2A6MEN1
SCHEMBL8470635 0.68 VHL (0.46) KDM4EHTTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
EP-3689981-A1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM Corporation (JP) 2020-08-05 EP disclosed
US-20200199385-A1 ACTIVE ENERGY RAY CURABLE-TYPE INK JET INK, LIGHT SHIELDING FILM, AND METHOD OF MANUFACTURING LIGHT SHIELDING FILM FUJIFILM CORPORATION (JP) 2020-06-25 US disclosed
EP-2502967-B1 Ink composition FUJIFILM SPECIALITY INK SYSTEMS LTD (GB) 2019-08-21 EP disclosed
EP-2412768-B1 Inkjet ink composition, inkjet recording method, and printed material FUJIFILM CORP (JP) 2019-01-23 EP disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
EP-2042573-A1 Ink composition FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
EP-2042563-A1 Photocurable coating composition, and overprint and process for producing same FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds GILEAD SCIENCES, INC. 2008-03-27 US disclosed
EP-0054233-B1 NOVEL BENZO(B)THIOPHENES, BENZO(B)FURANS, THIOCHROMANS AND CHROMANS, PROCESSES FOR THEIR PREPARATION AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1986-09-24 EP disclosed
EP-0054233-A1 Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them SCHERING CORPORATION (US) 1982-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds TYMP, PNP, PIKFYVE DNMT1 1512/4885CYP19A1 2704/4885KDM4E 1618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.