Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146820 | 0.94 | SKP2 (0.50) | SKP2MAOASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5146884 | 0.92 | SKP2 (0.48) | SKP2MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31556195 | 0.87 | SKP2 (0.50) | SKP2SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL718078 | 0.85 | TAAR1 (0.56) | SLC6A2SLC6A3 | |
| SCHEMBL29895824 | 0.84 | SLC6A2 (0.58) | SKP2MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15787360 | 0.84 | SLC6A2 (0.58) | SKP2MAOASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL857309 | 0.83 | TAAR1 (0.54) | SLC6A2SLC6A3 | |
| SCHEMBL17277454 | 0.82 | PNMT (0.50) | SKP2MAOAHRH1HTR2ATLR8 | |
| SCHEMBL15787340 | 0.81 | BACE1 (0.50) | SKP2MAOAHTR2ATLR8 | |
| SCHEMBL17866573 | 0.81 | SKP2 (0.60) | SKP2SLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221827-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| EP-0525360-B1 | Novel phenylacetamide derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1998-03-25 | — | — | EP | disclosed |
| US-5242944-A | Analgesics or antiinflammatory agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-09-07 | — | — | US | disclosed |
| EP-0525360-A2 | Novel phenylacetamide derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-02-03 | — | — | EP | disclosed |