Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605132 | 1.00 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1HPGDESR1 | |
| SCHEMBL7372514 | 0.89 | DDB1 (0.48) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7371671 | 0.84 | TDP1 (0.46) | ALDH1A1TSHRTDP1KMT2AMEN1 | |
| SCHEMBL8605725 | 0.75 | ELANE (0.41) | ALDH1A1TSHRTDP1KMT2AHTT | |
| SCHEMBL7362295 | 0.68 | GLA (0.45) | KDM4EALDH1A1TSHRTDP1KMT2A | |
| Phthalic Acid SCHEMBL27681760 | 0.66 | ALDH1A1 (0.70) | KDM4EHSD17B10ALDH1A1HPGDESR1 | |
| SCHEMBL9112320 | 0.66 | ALDH1A1 (0.55) | KDM4EHSD17B10ALDH1A1HPGDESR1 | |
| Alcohol SCHEMBL17255935 | 0.66 | HTT (0.70) | KDM4EHSD17B10ALDH1A1HPGDESR1 | |
| SCHEMBL124831 | 0.66 | ALDH1A1 (0.65) | KDM4EHSD17B10ALDH1A1HPGDESR1 | |
| Benzene SCHEMBL27314454 | 0.66 | ALDH1A1 (0.65) | KDM4EHSD17B10ALDH1A1HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826065-A1 | ENZYMATIC HYDROLYSIS OF 3,3-DIETHYL-4- (4-CARBOXY)PHENOXY]-2-AZETIDINONE ESTERS | Merck & Co., Inc. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996034975-A1 | ENZYMATIC HYDROLYSIS OF 3,3-DIETHYL-4-[(4-CARBOXY)PHENOXY]-2-AZETIDINONE ESTERS | MERCK & CO., INC. (US) | 1996-11-07 | — | — | WO | disclosed |
| US-5523233-A | Enzymatic hydrolysis of 3,3-diethyl-4-[(4-carboxy)phenoxy]-2-azetidinone esters | MERCK & CO., INC. (US) | 1996-06-04 | — | — | US | disclosed |