Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 10/20 | 0.46 |
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851131 | 0.90 | ST14 (0.57) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851341 | 0.82 | ST14 (0.66) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL852042 | 0.81 | ST14 (0.55) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851226 | 0.81 | ST14 (0.62) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851665 | 0.80 | ST14 (0.50) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851900 | 0.79 | ST14 (0.51) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL852041 | 0.79 | ST14 (0.54) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL852094 | 0.78 | ST14 (0.73) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851056 | 0.77 | ST14 (0.57) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851758 | 0.77 | ST14 (0.54) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |