Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 6/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436406 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL240029 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5182602 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8331267 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8509311 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL2010793 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL1994118 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL7752119 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL9393271 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL2636634 | 0.85 | PDPK1 (0.43) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322242-B1 | Adenosine derivatives | GLAXO GROUP LTD (GB) | 1998-04-01 | — | — | EP | disclosed |
| US-5032583-A | Cardiovascular disorders | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| EP-0322242-A2 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |