SCHEMBL8606927

SCHEMBL8606927

CN1/C(=C2\SC(=S)N(CC(=O)O)C2=O)Sc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 11/20 0.61
▸ KMT2A Q03164 11/20 0.61
▸ APEX1 P27695 3/20 0.59
▸ PTGES O14684 1/20 0.59
▸ POLB P06746 6/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ MAPT P10636 4/20 0.53
▸ MMP13 P45452 2/20 0.53
▸ CTDSP1 Q9GZU7 3/20 0.52
▸ USP2 O75604 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ BLM P54132 1/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ ALOX15 P16050 2/20 0.48
▸ ALOX12 P18054 2/20 0.48
▸ CASP1 P29466 2/20 0.48
▸ CASP7 P55210 2/20 0.48
▸ HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8606929 1.00 MEN1 (0.61) MEN1KMT2AAPEX1PTGESPOLB
SCHEMBL9651470 0.94 MEN1 (0.58) MEN1KMT2AAPEX1PTGESPOLB
SCHEMBL9651467 0.94 MEN1 (0.58) MEN1KMT2AAPEX1PTGESPOLB
SCHEMBL9054683 0.89 MEN1 (0.60) MEN1KMT2AAPEX1POLBSMN1; SMN2
SCHEMBL9054686 0.89 MEN1 (0.60) MEN1KMT2AAPEX1POLBSMN1; SMN2
SCHEMBL9191085 0.87 MEN1 (0.80) MEN1KMT2AAPEX1PTGESPOLB
SCHEMBL9191082 0.87 MEN1 (0.80) MEN1KMT2AAPEX1PTGESPOLB
SCHEMBL17069352 0.85 KMT2A (0.62) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL2333243 0.85 MEN1 (0.81) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL15995453 0.85 MEN1 (0.81) MEN1KMT2APOLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487010-B1 Improved sensitization of tabular grains with a zeromethine dye and a tetraazaindene DU PONT (US) 1996-03-20 — — EP claimed
EP-0487010-A1 Improved sensitization of tabular grains with a zeromethine dye and a tetraazaindene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-27 — — EP claimed
US-5108887-A Zeromethine merocyanine dyes as J-aggregating spectral sensitizers for tabular emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-28 — — US claimed
US-7468146-B2 Metal chalcogenide composite nano-particles and layers therewith AGFA-GEVAERT (BE) 2008-12-23 — — US disclosed
US-7468146-B2 Metal chalcogenide composite nano-particles and layers therewith AGFA-GEVAERT (BE) 2008-12-23 — — US disclosed
EP-1306719-B1 Silver halide photographic material showing improved latent image stability AGFA GEVAERT (BE) 2007-03-07 — — EP disclosed
EP-0627744-B1 Improved radiological system employing phospors of different densities STERLING DIAGNOSTIC IMAGING (US) 1998-03-18 — — EP disclosed
EP-0487010-B1 Improved sensitization of tabular grains with a zeromethine dye and a tetraazaindene DU PONT (US) 1996-03-20 — — EP disclosed
EP-0611457-B1 RADIOGRAPHIC MATERIALS WITH INCREASED UV SENSITIVITY DU PONT (US) 1996-02-14 — — EP disclosed
EP-0627744-A2 Improved radiological system employing phospors of different densities E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-07 — — EP disclosed
US-5367172-A Radiological system employing phosphors of different densities E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-22 — — US disclosed
EP-0611457-A1 RADIOGRAPHIC MATERIALS WITH INCREASED UV SENSITIVITY. DU PONT (US) 1994-08-24 — — EP disclosed
WO-1993009468-A1 RADIOGRAPHIC MATERIALS WITH INCREASED UV SENSITIVITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 — — WO disclosed
US-5169748-A X-rays intensifying screen having phosphor emitters and photosensitive substrates with coatings containing azo-pyrazolone dyes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-08 — — US disclosed
EP-0487010-A1 Improved sensitization of tabular grains with a zeromethine dye and a tetraazaindene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-27 — — EP disclosed
US-5108887-A Zeromethine merocyanine dyes as J-aggregating spectral sensitizers for tabular emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-28 — — US disclosed
US-5035990-A Containing a thione in a tabular grain silver halide emulsion dispersed in binder E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-30 — — US disclosed
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