SCHEMBL9191082

SCHEMBL9191082

CCN1/C(=C2\SC(=S)N(CC(=O)O)C2=O)Sc2ccccc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 13/20 0.80
▸ KMT2A Q03164 13/20 0.80
▸ SMN1; SMN2 Q16637 2/20 0.73
▸ POLB P06746 4/20 0.69
▸ MAPT P10636 4/20 0.62
▸ MMP13 P45452 2/20 0.62
▸ APEX1 P27695 2/20 0.58
▸ PTGES O14684 1/20 0.58
▸ LMNA P02545 1/20 0.57
▸ HPGD P15428 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ CASP1 P29466 1/20 0.57
▸ CASP7 P55210 1/20 0.57
▸ HSD17B10 Q99714 1/20 0.57
▸ ALDH1A1 P00352 3/20 0.56
▸ GFER P55789 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.54
▸ NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9191085 1.00 MEN1 (0.80) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL29959615 0.95 MEN1 (0.71) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL7019338 0.89 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL10036060 0.89 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8887899 0.89 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL10661708 0.89 MEN1 (0.76) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL14620886 0.88 MEN1 (0.74) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8606929 0.87 MEN1 (0.61) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8606927 0.87 MEN1 (0.61) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL11267198 0.87 MEN1 (0.73) MEN1KMT2ASMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4128422-A Cyclopropenone vesicular imaging composition, element and process EASTMAN KODAK COMPANY (US) 1978-12-05 — — US claimed
US-7468146-B2 Metal chalcogenide composite nano-particles and layers therewith AGFA-GEVAERT (BE) 2008-12-23 — — US disclosed
US-7468146-B2 Metal chalcogenide composite nano-particles and layers therewith AGFA-GEVAERT (BE) 2008-12-23 — — US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
EP-0333435-B1 High contrast photographic element and emulsion and process for their use EASTMAN KODAK CO (US) 1995-12-13 — — EP disclosed
EP-0345025-B1 High contrast photographic recording material and emulsion and process for their development EASTMAN KODAK CO (US) 1994-03-09 — — EP disclosed
US-5126227-A High speed, low fogging, quality, efficiency EASTMAN KODAK COMPANY (US) 1992-06-30 — — US disclosed
US-5104769-A Negative working silver halide and arylhydrazide nucleating agent EASTMAN KODAK COMPANY (US) 1992-04-14 — — US disclosed
US-5041355-A High contrast photographic element including an aryl sulfonamidophenyl hydrazide containing ethyleneoxy groups EASTMAN KODAK COMPANY (US) 1991-08-20 — — US disclosed
US-4988604-A Silver halide elements for development with alkaline agent, multilayer, nucleation agent EASTMAN KODAK COMPANY (US) 1991-01-29 — — US disclosed
US-4975354-A Silver halide developed in presence of a hydrazone using an aqueous alkaline solution; black and white photography; lithography EASTMAN KODAK COMPANY (US) 1990-12-04 — — US disclosed
EP-0209011-B1 HIGH CONTRAST PHOTOGRAPHIC ELEMENTS EXHIBITING STABILIZED SENSITIVITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-11-07 — — EP disclosed
EP-0209012-B1 HIGH CONTRAST PHOTOGRAPHIC ELEMENTS EXHIBITING REDUCED PEPPER FOG EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-11-07 — — EP disclosed
US-4912016-A Aromatic hydrazide EASTMAN KODAK COMPANY (US) 1990-03-27 — — US disclosed
US-4724201-A SILVER HALIDE EMULSION AND A SENSITIZING DYE HAVING A CYCLODEXTRIN SUBSTITUENT; PHOTOGRAPHIC FILM FUJI PHOTO FILM CO., LTD. (JP) 1988-02-09 — — US disclosed
US-4650746-A HYDRAZIDE NUCLEATING AGENTS EASTMAN KODAK COMPANY (US) 1987-03-17 — — US disclosed
US-4618574-A AN ARYLHYDRAZIDE, A POLHYDROXYBENZENE AND A CARBOXYALKYL3H-THIAZOLINE-2-THIONE EASTMAN KODAK COMPANY (US) 1986-10-21 — — US disclosed
US-4560638-A Halftone imaging silver halide emulsions, photographic elements, and processes which employ novel arylhydrazides EASTMAN KODAK COMPANY (US) 1985-12-24 — — US disclosed
US-4128422-A Cyclopropenone vesicular imaging composition, element and process EASTMAN KODAK COMPANY (US) 1978-12-05 — — US disclosed
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