SCHEMBL8607116

SCHEMBL8607116

CCCCCCCCCCCCCCOC(=O)[C@@](CCCCN)(NCCCCCCCCCC)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
EPHX1 P07099 1/20 0.38
HTT P42858 1/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
ACHE P22303 6/20 0.37
HTR2C P28335 1/20 0.37
NAAA Q02083 1/20 0.36
SLC6A5 Q9Y345 2/20 0.36
EPHX2 P34913 2/20 0.36
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608138 1.00 MEN1 (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL8608063 0.97 MEN1 (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL8610694 0.91 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL6671188 0.75 GNAI3 (0.44) MEN1KMT2AEPHX1GNAI3GNAO1
SCHEMBL27362196 0.75 CYP4F2 (0.50) MEN1KMT2AEPHX1HTR2CNAAA
SCHEMBL27898238 0.75 CYP4F2 (0.50) MEN1KMT2AEPHX1HTR2CNAAA
SCHEMBL29002362 0.74 EPHX1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL5853008 0.72 EPHX1 (0.42) EPHX1ACHEHTR2CNAAAHCAR2
SCHEMBL26642624 0.71 EPHX1 (0.41) MEN1MAPTKMT2AATML3MBTL1
Bromide SCHEMBL10571114 0.71 EPHX1 (0.49) EPHX1ACHENAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652209-B1 Derivatives of N-epsilon alkoxy-or alkenoxy-carbonyl lysine, their preparation and use in cosmetic, pharmaceutical, hygiene or alimentary compositions OREAL (FR) 1998-04-08 EP claimed
EP-0652209-A1 Derivatives of N-episilon alkoxy-or alkenoxy-carbonyl lysine, their preparation and use in cosmetic, pharmaceutical, hygiene or alimentary compositions L'OREAL (FR) 1995-05-10 EP claimed
EP-0652209-B1 Derivatives of N-epsilon alkoxy-or alkenoxy-carbonyl lysine, their preparation and use in cosmetic, pharmaceutical, hygiene or alimentary compositions OREAL (FR) 1998-04-08 EP disclosed
EP-0652209-A1 Derivatives of N-episilon alkoxy-or alkenoxy-carbonyl lysine, their preparation and use in cosmetic, pharmaceutical, hygiene or alimentary compositions L'OREAL (FR) 1995-05-10 EP disclosed