Methylpiperazine

Methylpiperazine

SCHEMBL8607131

CN1CCNCC1.NC(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CHKA P35790 1/20 0.38
PHGDH O43175 1/20 0.37
CYP1A2 P05177 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
CHRNB3 Q05901 1/20 0.37
CHRNA6 Q15825 1/20 0.37
SIGMAR1 Q99720 2/20 0.36
OPRD1 P41143 1/20 0.35
ACHE P22303 1/20 0.35
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL28887896 0.92 CA2 (0.41) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL16669183 0.90 CA2 (0.42) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL1681596 0.87 CYP1A2 (0.44) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL7487241 0.87 CA2 (0.41) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL27895941 0.85 CA2 (0.39) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL28060474 0.85 CYP1A2 (0.42) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL9400626 0.85 CA2 (0.39) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL28536686 0.85 PHGDH (0.46) CA2CA12CA1CA9PHGDH
Methylpiperazine SCHEMBL7570599 0.84 PHGDH (0.38) CA2CA12CA1CA9CHKA
Methylpiperazine SCHEMBL9753809 0.83 PHGDH (0.44) CA2CA12CA1CA9PHGDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109536087-B Optical pressure-sensitive adhesive and preparation method thereof 苏州凡赛特材料科技有限公司 2021-03-19 CN disclosed
EP-0826032-A1 BIOTECHNICAL PRODUCTION PROCESS OF PIPERAZINE R-$g(a)-CARBOXYLIC ACIDS AND PIPERAZINE S-$g(a)-CARBOXYLIC ACID AMIDE LONZA AG (CH) 1998-03-04 EP disclosed
WO-1996035775-A1 BIOTECHNICAL PRODUCTION PROCESS OF PIPERAZINE R-α-CARBOXYLIC ACIDS AND PIPERAZINE S-α-CARBOXYLIC ACID AMIDE LONZA AG (CH) 1996-11-14 WO disclosed