SCHEMBL8607136

SCHEMBL8607136

Cc1c(C)c2c(c(C)c1[SiH3])C(=O)N(C)C2=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13865236 0.82 CASP3 (0.36) MAPTCASP3
SCHEMBL2704330 0.74 CASP3 (0.35) MAPTCASP3
SCHEMBL10137978 0.68 MAPT (0.32) MAPTCASP3
SCHEMBL17190540 0.68 MAPT (0.32) MAPTCASP3
SCHEMBL15031169 0.67 CASP3 (0.34) MAPTCASP3
SCHEMBL17427805 0.67
SCHEMBL17897616 0.67 MAPT (0.33) MAPTCASP3
SCHEMBL18694996 0.66
SCHEMBL14444942 0.65 MEN1 (0.34) MAPTCASP3
SCHEMBL18405814 0.64 MAPT (0.30) MAPTCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608484-B1 Reusable, positive-charging organic photoconductor containing phthalocyanine pigment, hydroxy binder and silicon stabilizer with superior surface release characteristics HEWLETT PACKARD CO (US) 1998-03-25 EP disclosed
EP-0608484-A1 Reusable, positive-charging organic photoconductor containing phthalocyanine pigment, hydroxy binder and silicon stabilizer with superior surface release characteristics Hewlett-Packard Company (US) 1994-08-03 EP disclosed
US-5320923-A For laser printers; improved surface release for better toner transfer HEWLETT-PACKARD COMPANY (US) 1994-06-14 US disclosed