Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529249 | 0.86 | PTPN1 (0.39) | PTPN1CNR1KDM4EALDH1A1TLR8 | |
| SCHEMBL6706314 | 0.75 | KDM4E (0.33) | PTPN1KDM4EALDH1A1 | |
| SCHEMBL15733045 | 0.69 | PTPN1 (0.54) | PTPN1ALDH1A1MEN1KMT2A | |
| SCHEMBL15732842 | 0.65 | PTPN1 (0.60) | PTPN1CNR1 | |
| SCHEMBL15732974 | 0.64 | PTPN1 (0.63) | PTPN1CNR1 | |
| SCHEMBL15733081 | 0.64 | PTPN1 (0.63) | PTPN1CNR1 | |
| SCHEMBL15732985 | 0.64 | PTPN1 (0.63) | PTPN1CNR1 | |
| SCHEMBL9754870 | 0.63 | ALDH1A1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL10608915 | 0.62 | PTPN1 (0.50) | PTPN1CNR1ALDH1A1 | |
| SCHEMBL5602078 | 0.62 | KDM4E (0.33) | PTPN1KDM4EALDH1A1TLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741794-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-21 | — | — | US | disclosed |
| EP-0620813-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |