Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605036 | 0.86 | HTR2C (0.55) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL8606286 | 0.82 | HTR2C (0.70) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL16467962 | 0.81 | HTR2C (0.76) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3652770 | 0.81 | HTR2C (0.76) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL2389760 | 0.79 | HTR2C (0.64) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL31316158 | 0.78 | HTR2C (0.72) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL4052931 | 0.78 | HTR2C (0.72) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL4431805 | 0.78 | HTR2C (0.72) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL21384306 | 0.77 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1AGTR2 | |
| SCHEMBL4677056 | 0.77 | HTR2C (1.00) | HTR2CHCRTR2CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789595-A | ANTICOAGULANTS | TERUMO KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0790247-A1 | TETRAHYDROISOQUINOLINE DERIVATIVE AND MEDICINAL PREPARATION CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |