Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607749 | 0.89 | PTGS1 (0.39) | PTGS1PTGS2RXFP1HTR2AHTR2C | |
| SCHEMBL8608469 | 0.86 | PTGS1 (0.34) | PTGS1PTGS2RXFP1CREBBP | |
| SCHEMBL8606176 | 0.82 | PTGS1 (0.40) | PTGS1PTGS2RXFP1HTR2AHTR2C | |
| SCHEMBL8609477 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL8605302 | 0.81 | PTGS1 (0.39) | PTGS1PTGS2RXFP1HTR2AHTR2C | |
| SCHEMBL8609715 | 0.79 | PTGS1 (0.36) | PTGS1PTGS2RXFP1DHODHCREBBP | |
| SCHEMBL9753569 | 0.78 | PTGS1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL8607312 | 0.78 | RXFP1 (0.32) | PTGS1PTGS2RXFP1 | |
| SCHEMBL2505187 | 0.72 | PTGS1 (0.51) | PTGS1PTGS2RXFP1DHODHCREBBP | |
| SCHEMBL8606992 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716964-A | BRAIN DISORDERS; ANTIISCHEMIC AGENTS | G.D. SEARLE & CO. (US) | 1998-02-10 | — | — | US | disclosed |