Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607708 | 0.89 | ALDH1A2 (0.31) | KDM4ENPC1ALDH1A1TP53RAB9A | |
| SCHEMBL8605892 | 0.84 | KDM4E (0.31) | KDM4ENPC1ALDH1A1TP53NFKB1 | |
| SCHEMBL8607463 | 0.82 | PTGS1 (0.37) | — | |
| SCHEMBL8607404 | 0.81 | ALDH1A2 (0.33) | KDM4ENPC1ALDH1A1TP53NFKB1 | |
| SCHEMBL8608781 | 0.79 | ALDH1A2 (0.32) | KDM4ENPC1ALDH1A1TP53NFKB1 | |
| SCHEMBL9753486 | 0.79 | APP (0.35) | — | |
| SCHEMBL9753378 | 0.77 | — | — | |
| SCHEMBL8608664 | 0.77 | NPC1 (0.31) | KDM4ENPC1ALDH1A1TP53NFKB1 | |
| SCHEMBL8607749 | 0.70 | PTGS1 (0.39) | — | |
| SCHEMBL9753722 | 0.70 | APP (0.32) | KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716964-A | BRAIN DISORDERS; ANTIISCHEMIC AGENTS | G.D. SEARLE & CO. (US) | 1998-02-10 | — | — | US | disclosed |