Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099903 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRCA2 | |
| SCHEMBL27809448 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL4880627 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL1038859 | 0.82 | — | — | |
| SCHEMBL9173076 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL28272544 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL8368012 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL17526574 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL17526573 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNATDP1TSHRCYP3A4 | |
| SCHEMBL5674144 | 0.79 | TSHR (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611783-B1 | Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0611783-A1 | Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives | CIBA-GEIGY AG (CH) | 1994-08-24 | — | — | EP | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |