Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559631 | 0.82 | TP53 (0.39) | TP53TSHRGAALMNAPOLB | |
| SCHEMBL8606609 | 0.79 | STAT3 (0.49) | STAT3SMYD3RAB9ATSHRSTAT1 | |
| SCHEMBL7554639 | 0.74 | TP53 (0.38) | TP53TSHRGAALMNAPOLB | |
| SCHEMBL8606653 | 0.74 | RAB9A (0.56) | STAT3SMYD3TP53RAB9AS1PR3 | |
| SCHEMBL7556634 | 0.73 | MCOLN3 (0.46) | TP53TSHRGAALMNAPOLB | |
| SCHEMBL8607579 | 0.73 | SMYD3 (0.47) | STAT3SMYD3RAB9AS1PR3S1PR1 | |
| SCHEMBL8608679 | 0.73 | STAT3 (0.46) | STAT3SMYD3RAB9ATSHRSTAT1 | |
| SCHEMBL7552723 | 0.72 | GAA (0.45) | TP53TSHRGAAPOLB | |
| SCHEMBL7552958 | 0.71 | TP53 (0.38) | TP53TSHRGAAPOLB | |
| SCHEMBL8607786 | 0.71 | STAT3 (0.45) | STAT3SMYD3RAB9ATSHRSTAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |