Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608650 | 0.88 | GAA (0.68) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8608313 | 0.87 | GAA (0.54) | GAAMEN1KMT2AALDH1A1XBP1 | |
| SCHEMBL28287652 | 0.86 | GAA (0.54) | GAAMEN1KMT2AALDH1A1XBP1 | |
| SCHEMBL8635233 | 0.84 | GAA (0.67) | GAAMEN1KMT2AALDH1A1XBP1 | |
| SCHEMBL8608828 | 0.83 | GAA (0.65) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8606883 | 0.81 | GAA (0.66) | GAAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL8606000 | 0.80 | GAA (0.61) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL30206727 | 0.77 | NR1H4 (0.48) | GAAALDH1A1XBP1MAPK1HTT | |
| SCHEMBL265814 | 0.77 | NR1H4 (0.48) | GAAALDH1A1XBP1MAPK1HTT | |
| SCHEMBL8606755 | 0.76 | HPGD (0.52) | GAAMEN1KMT2AALDH1A1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |