SCHEMBL8608162

SCHEMBL8608162

CCOCCCCCC(OC(=O)c1ccc(-c2ccc(OC(C)=O)cc2)cc1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HSD17B10 Q99714 1/20 0.40
RARB P10826 5/20 0.37
HDAC1 Q13547 3/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC7 Q8WUI4 2/20 0.37
HDAC10 Q969S8 2/20 0.37
HDAC11 Q96DB2 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
HDAC9 Q9UKV0 2/20 0.37
HDAC5 Q9UQL6 2/20 0.37
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979860 0.97 KMT2A (0.50) KMT2AL3MBTL1HSD17B10LMNAGAA
SCHEMBL8975370 0.97 KMT2A (0.50) KMT2AL3MBTL1HSD17B10LMNAGAA
SCHEMBL8610193 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL8664858 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7755271 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7750663 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7753926 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7755297 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7754274 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3
SCHEMBL7753969 0.88 NPC1 (0.50) KMT2ARARBHDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497297-B1 Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL CO (JP) 1998-04-08 EP disclosed
US-5364560-A Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1994-11-15 US disclosed
EP-0484849-B1 Optically active alcohol, process for producing same and liquid crystal compound using same MITSUBISHI GAS CHEMICAL CO (JP) 1994-08-31 EP disclosed
US-5264150-A Fluorinated, ether aromatic ester compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-11-23 US disclosed
EP-0497297-A2 Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-05 EP disclosed
EP-0484849-A1 Optically active alcohol, process for producing same and liquid crystal compound using same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-05-13 EP disclosed