Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975370 | 1.00 | KMT2A (0.50) | KMT2AL3MBTL1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8608162 | 0.97 | KMT2A (0.47) | KMT2AL3MBTL1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8166399 | 0.90 | KMT2A (0.42) | KMT2AL3MBTL1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8082375 | 0.86 | ESR1 (0.42) | SMN1; SMN2HPGDNPC1LMNAALDH1A1 | |
| SCHEMBL8082379 | 0.86 | ESR1 (0.42) | SMN1; SMN2HPGDNPC1LMNAALDH1A1 | |
| SCHEMBL8979680 | 0.86 | ESR1 (0.42) | SMN1; SMN2HPGDNPC1LMNAALDH1A1 | |
| SCHEMBL7754274 | 0.85 | NPC1 (0.50) | KMT2ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL7755297 | 0.85 | NPC1 (0.50) | KMT2ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL8610193 | 0.85 | NPC1 (0.50) | KMT2ASMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL7750663 | 0.85 | NPC1 (0.50) | KMT2ASMN1; SMN2NPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559088-B1 | Dioxane type liquid crystal substance | MITSUBISHI GAS CHEMICAL CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5482651-A | ANTIFERROELECTRIC | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0559088-A1 | Dioxane type liquid crystal substance | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-09-08 | — | — | EP | disclosed |