Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071012 | 0.95 | KDM4E (0.48) | KDM4EEPHX1ALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL3064740 | 0.95 | KDM4E (0.48) | KDM4EEPHX1ALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL7533440 | 0.95 | KDM4E (0.48) | KDM4EEPHX1ALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL7525000 | 0.94 | KDM4E (0.46) | KDM4EEPHX1ALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL3055428 | 0.86 | ABCB1 (0.45) | KDM4EALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL27493475 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1L3MBTL1ABCB1USP2 | |
| Maleic Acid SCHEMBL7526315 | 0.79 | EPHX2 (0.40) | KDM4EALDH1A1ABCB1EPHX2USP2 | |
| Fumaric Acid SCHEMBL7526322 | 0.79 | EPHX2 (0.40) | KDM4EALDH1A1ABCB1EPHX2USP2 | |
| Hydrochloric Acid SCHEMBL3077107 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1L3MBTL1ABCB1USP2 | |
| SCHEMBL3064749 | 0.77 | KDM4E (0.54) | KDM4EEPHX1ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000251-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1997-01-03 | — | — | WO | disclosed |