⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154 | 0.94 | — | — | |
| SCHEMBL251442 | 0.94 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7542079 | 0.89 | TSHR (0.32) | — | |
| SCHEMBL15674477 | 0.89 | — | — | |
| SCHEMBL5140016 | 0.89 | — | — | |
| SCHEMBL15821191 | 0.89 | — | — | |
| SCHEMBL11864412 | 0.89 | — | — | |
| SCHEMBL21641734 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL22129249 | 0.89 | — | — | |
| SCHEMBL18304645 | 0.89 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344346-A | Heterocyclic compounds and their use | 武田药品工业株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-115515943-B | Oxadiazole derivatives | 住友制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118317965-A | Adenosine receptor antagonists | 交信医药研发公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118290408-A | Heterocyclic compounds and their use | 武田药品工业株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-115335369-B | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271297-A | Heterocyclic compounds and their use | 武田药品工业株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271298-A | Heterocyclic compounds and their use | 武田药品工业株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-114008037-B | Heterocyclic compounds as KRAS G12C inhibitors | 广东新契生物医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-112135830-B | Oxo-substituted compounds | 住友制药株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-118084923-A | Cyclic compounds as LRRK2 kinase inhibitors and methods of making the same | 中国科学院上海有机化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| EP-2832725-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-04 | — | — | EP | disclosed |
| US-8273745-B2 | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC (JP) | 2012-09-25 | — | — | US | disclosed |
| EP-2094662-B1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC (JP) | 2012-04-11 | — | — | EP | disclosed |
| EP-2433973-A1 | CURABLE RESIN COMPOSITION, TRANSPARENT LAMINATE AND METHOD FOR PRODUCING SAME | Asahi Glass Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-20100009991-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-1948639-A2 | NOVEL CARBOCYCLIC FUSED CYCLIC AMINES | F. Hoffmann-la Roche AG (CH) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054453-A2 | CARBOCYCLIC FUSED CYCLIC AMINES AS INHIBITORS OF THE COAGULATION FACTOR XA | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006045579-A1 | METHOD FOR PRODUCING POLYOXYMETHYLENES USING A HETEROPOLY ACID AS THE CATALYST | TICONA GMBH (DE) | 2006-05-04 | — | — | WO | disclosed |
| EP-0597976-A1 | IMPROVED CALCIUM CARBOXYLATE ANTIWEAR ADDITIVES. | EXXON CHEMICAL PATENTS INC (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993004150-A1 | IMPROVED CALCIUM CARBOXYLATE ANTIWEAR ADDITIVES | EXXON CHEMICAL PATENTS INC. (US) | 1993-03-04 | — | — | WO | disclosed |