Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.75 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | OSBP | P22059 | 1/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.65 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.63 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426770 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27320877 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27320821 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28088866 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27320857 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL11423844 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27883156 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| Ethane SCHEMBL27501171 | 0.99 | POLA1 (0.74) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL25351944 | 0.99 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL2134010 | 0.99 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548344-B1 | COLLAGEN COMPOSITES FOR CONTROLLED DRUG RELEASE | VITAPHORE CORP (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0548344-A4 | COLLAGEN COMPOSITES FOR CONTROLLED DRUG RELEASE | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0548344-A1 | COLLAGEN COMPOSITES FOR CONTROLLED DRUG RELEASE | VITAPHORE CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1993000890-A1 | COLLAGEN COMPOSITES FOR CONTROLLED DRUG RELEASE | VITAPHORE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |