Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.77 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | OSBP | P22059 | 1/20 | 0.66 |
| ▸ | RORC | P51449 | 1/20 | 0.66 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.66 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954232 | 1.00 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27319635 | 1.00 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL25351944 | 1.00 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3954234 | 1.00 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27320877 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL11426770 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27883156 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27320857 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL8608992 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28088866 | 0.99 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10245272-B2 | Transmembrane penetration enhancer | KRAVCHENKO IRYNA (US) | 2019-04-02 | — | — | US | claimed |
| US-20120101088-A1 | Transmembrane Penetration Enhancer | KRAVCHENKO IRYNA (US) | 2012-04-26 | — | — | US | claimed |
| US-10245272-B2 | Transmembrane penetration enhancer | KRAVCHENKO IRYNA (US) | 2019-04-02 | — | — | US | disclosed |
| US-8361494-B2 | Biomimetic iron-oxide-containing lipoprotein and related materials | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120101088-A1 | Transmembrane Penetration Enhancer | KRAVCHENKO IRYNA (US) | 2012-04-26 | — | — | US | disclosed |
| US-20090035223-A1 | BIOMIMETIC IRON-OXIDE-CONTAINING LIPOPROTEIN AND RELATED MATERIALS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-02-05 | — | — | US | disclosed |
| WO-2007106683-A2 | BIOMIMETIC IRON-OXIDE-CONTAINING LIPOPROTEIN AND RELATED MATERIALS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-09-20 | — | — | WO | disclosed |
| US-4999348-A | Sustained Release and Enhanced Penetration of Vitamin A | ESTEE LAUDER INC. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4966205-A | Method and apparatus for charging transparent material | POLA CHEMICAL INDUSTRIES LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4040784-A | Method for checking the accuracy of a test, using a serum-soluble cholesterol compound | MONOBIND, INC., A CORP. OF CA. | 1977-08-09 | — | — | US | disclosed |