Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.73 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.73 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.73 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.73 |
| ▸ | CXCR2 | P25025 | 9/20 | 0.60 |
| ▸ | PLK1 | P53350 | 6/20 | 0.48 |
| ▸ | CCR6 | P51684 | 4/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PRKX | P51817 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587558 | 1.00 | ABCC9 (0.73) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL4258934 | 0.84 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL6024203 | 0.84 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL6106234 | 0.84 | CXCR2 (0.81) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL8670505 | 0.83 | ABCC9 (0.70) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL8670509 | 0.83 | ABCC9 (0.70) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL8585548 | 0.83 | CXCR2 (0.67) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL7347226 | 0.79 | PLK1 (0.67) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL8372683 | 0.79 | PLK1 (0.67) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 | |
| SCHEMBL8588827 | 0.79 | CXCR2 (0.62) | ABCC9ABCC8KCNJ11KCNJ8CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840764-A | SMOOTH MUSCLE RELAXANTS FOR TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1998033763-A1 | SUBSTITUTED HYDROXY-ANILINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-06 | — | — | WO | disclosed |