Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 7/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.64 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.64 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.59 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.59 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.59 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802413 | 0.87 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8192778 | 0.85 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7484219 | 0.85 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7482751 | 0.84 | GRIA1 (0.69) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610087 | 0.84 | GRIK1 (0.82) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8609152 | 0.83 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7480413 | 0.82 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9092206 | 0.81 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7811014 | 0.80 | SLC22A6 (0.77) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7478349 | 0.80 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |