Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694774 | 0.89 | POLB (0.62) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL29486954 | 0.89 | NPC1L1 (0.49) | POLBNPC1L1USP2LMNAALDH1A1 | |
| SCHEMBL26653373 | 0.89 | NPC1L1 (0.49) | POLBNPC1L1USP2LMNAALDH1A1 | |
| SCHEMBL26653376 | 0.89 | NPC1L1 (0.49) | POLBNPC1L1USP2LMNAALDH1A1 | |
| SCHEMBL26783767 | 0.88 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL26785093 | 0.88 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL24358440 | 0.87 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL26783736 | 0.87 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL26783733 | 0.87 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA | |
| SCHEMBL26653694 | 0.87 | NPC1L1 (0.51) | POLBPOLA1NPC1L1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814581-A | PLANT GROWTH PROMOTERS | NIPPON ZEON CO., LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0777965-A1 | PLANT GROWTH PROMOTER | NIPPON ZEON CO., LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0080381-B1 | HOMOBRASSINOLIDE, AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0080381-A2 | Homobrassinolide, and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-01 | — | — | EP | disclosed |