Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 18/20 | 0.73 |
| ▸ | GRIA2 | P42262 | 18/20 | 0.73 |
| ▸ | GRIA3 | P42263 | 18/20 | 0.73 |
| ▸ | GRIA4 | P48058 | 18/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 13/20 | 0.71 |
| ▸ | GRIK2 | Q13002 | 13/20 | 0.71 |
| ▸ | GRIK3 | Q13003 | 13/20 | 0.71 |
| ▸ | GRIK4 | Q16099 | 13/20 | 0.71 |
| ▸ | GRIK5 | Q16478 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609084 | 0.90 | GRIA1 (0.81) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8608737 | 0.89 | GRIA1 (0.87) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7665861 | 0.89 | GRIA1 (0.78) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8609391 | 0.89 | GRIA1 (0.80) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7973994 | 0.88 | GRIA1 (0.74) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8609954 | 0.88 | GRIA1 (0.78) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7480169 | 0.88 | GRIA1 (0.71) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL24312933 | 0.87 | GRIA1 (0.77) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7668608 | 0.84 | GRIA1 (0.78) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8675872 | 0.83 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |